Category: news

Job offer: NGS TECHNOLOGIST (ref. 2021/134) [CLOSED]

JOB DESCRIPTION:

The IGTP needs a highly motivated NGS Technologist to contribute to accelerate the access to precision medicine in the field of cancer.

The successful candidate will join a multidisciplinary and dynamic group integrated by academic researchers and a private entrepreneurship, based in the IGTP at the Can Ruti Campus in Badalona. The major goal of the project is the development of genomic tools, including both innovative wet lab methods and sophisticated bioinformatic tools, to analyze genetic and epigenetic variations in cancer and other diseases.

QUALIFICATIONS AND EXPERIENCE:

The applicant must have the following qualifications:

  • Wet-lab experience working with DNA/RNA related technologies.
  • Experience working with NGS and/or technology development.
  • Experience in a core facility, molecular diagnostics laboratory, or biotechnology. company is also a plus.
  • Previous experience in quality assessment is a plus.
  • Friendly, collaborative mindset, ability to multi-task and to work effectively.

The following items will be of value:

  • Higher degree training cycle in some field of life sciences or health.
  • It will be valued positive uyniversity degree in life sciences or related fields.
  • High organizational skills.
  • Very strong motivation and commitment, proactive mindset, getting-things-done attitude.
  • Written and oral communication skills in English.
  • Computational skills (Office, content management systems, etc.).

Persons with a degree of disability equal to or greater than 33 per 100, as accredited by the Spanish Autonomous Regions or the State Administration, or who have been declared to have a total permanent disability in a different profession through a resolution of the National Institute of Social Security, while retaining functional capacity for the completion of the tasks of the post will be positively considered.

MAIN RESPONSIBILITIES:

The specific tasks will be:

  • Development and execution of complex library preparation protocols (manually and/or with automated systems).
  • Optimization and testing of new protocols.
  • Troubleshooting of technical problems in the sample preparation and sequencing workflows.
  • Customer support and productive interaction with researchers with diverse backgrounds.
  • Quality management and implementation of standard procedures.

WHAT WE OFFER:

  • Contract for project with full time position.
  • Gross annual remuneration inherent in the position covered by this call, will be set according to the amount awarded for the grant awarded, distributed in 12 payments.
  • Flexible payment (childminding vouchers).
  • 23 days holiday and 5 days for personal matters.
  • Training capsules by the company.
  • Be part of an excellent multidisciplinary research center with the HRS4R badge.

FOR MORE INFORMATION:

For more information see the link: www.germanstrias.org/

APPLICATIONS:

Those interested must send a letter of motivation explaining their interest in the post, a CV and the contacts of 2-3 referees to the address seleccio@igtp.cat

APPLICATIONS THAT DO NOT INCLUDE THE REFERENCE CODE IN THE SUBJECT LINE WILL NOT BE CONSIDERED

After pre-selection the short list of candidates will be invited for interview.

2021/134 NGS TECHNOLOGIST (PDF 499,90 Kb)

The IGTP takes part in European Performance Science Night 2021

The Germans Trias i Pujol Research Institute (IGTP) has participated in a ground-breaking event to bring art and science together for European Performing Science Night with results that left nobody indifferent. The Fundació Èpica la Fura dels Baus led the project which involved artists and scientists from the IGTP and four international universities.

Three groups from the IGTP took part: The Innovation in Respiratory Infections and Tuberculosis Diagnosis group led by Dr José Dominguez; the Viral Immune Evasion and Vaccines (VIRIEVAC) research group of IrsiCaixa, led by Dr Julia García-Prado and the Epigenetics of Cell Differentiation and Cancer group, led by Dr Miguel Angel Peinado. And an intensive and exhilarating process got underway. Starting in July, the scientists presented three of the seven challenges put to the workshop team. Researchers from each group joined artists and technicians who worked intensively for two weeks to produce a performance piece using the language of the Fura dels Baus.

More info at:

Science at the IGTP becomes performance art in the hands of the Fura dels Baus’s Epicalab

Friday, 29 November 2019 – Research

W are one of the two groups at the IGTP participating in the workshop “Complex Systems” organized by the Èpica Foundation. The experience is a first for the IGTP and has meant that art and science have worked together to produce results for both of them. Èpica is a space for interdisciplinary learning and training for the performing arts run by the Fura dels Baus. The results of the workshop are based on research projects from the IGTP and will be shown this Friday and Saturday 29 and 30 November at the Èpica headquarters in Badalona.

More info at:

JOB OFFER: EPIGENOMICS BIOINFORMATICIAN (ref. 2019/29) [CLOSED]

Main Responsibilities

The individual in this position will be responsible for computational biology and bioinformatics support of genome-scale projects using advanced genomic technologies including in-house developed NGS methods. The major goal of the project is the obtention of genome-scale maps of epigenetic variation in human populations and disease. The project is highly collaborative and provides the opportunity to interact with investigators in different disciplines, including computational and experimental biology.

Primary duties will include, but will not be limited, to the design and implementation of algorithms to map, annotate, integrate and organize data generated by next generation sequencing instruments, and  downstream statistical analyses and validation. Duties will also include data-mining on high-throughput data sets and development of tools for data analysis, integration and visualization.

Requirements

Background: PhD in Bioinformatics, Computer Science, Biology,  Mathematics, or a related field. Experience in biomedical computing. Proven proficiency in the management of Biological Databases, programming languages (R, Python, etc.) and biostatistics methods is required.

What we offer

  • A contract for a period of 12 months with possibility of extension
  • Competitive salary according to qualifications and experience
  • Integration in a collaborative scientific network devoted to high quality research in the field of cancer genomics and epigenomics
  • Dynamic interaction with other leading cancer research groups
  • Interaction with other bioinformatics groups within and outside of the institution
  • Possibility for career advancement and attendance to specialized training courses and scientific meetings

Additional information

For more information on the research of the Mechanisms of Cancer and Cell Differentiation group visit the web page at http://maplab.cat or write to Miguel A. Peinado at mpeinado@igtp.cat.

Deadline for applications: 24 March 2019

How to apply

Interested applicants should send the following documents to rrhh@igtp.cat and mpeinado@igtp.cat:

  • A short statement of motivation
  • A CV including your contact details
  • Names, email and telephone numbers of two referees

 

PLEASE INDICATE THE REFERENCE 2019/29 in the subject of the mail.

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JOB POSITION: Scientific Coordinator (ref. 2019/24) [CLOSED]

We are seeking an enthusiastic Scientific Coordinator to manage a collaborative project “GEUS” aimed to bring advances in Genomics and Epigenomics to research and medical applications. The project is a partnership between academic institutions and the biotech industry.

Continue reading “JOB POSITION: Scientific Coordinator (ref. 2019/24) [CLOSED]”

Aging-like Spontaneous Epigenetic Silencing Facilitates Wnt Activation, Stemness, and BrafV600E-Induced Tumorigenesis

Tao Y, Kang B, Petkovich DA, Bhandari YR, In J, Stein-O’Brien G, Kong X, Xie W, Zachos N, Maegawa S, Vaidya H, Brown S, Chiu Yen RW, Shao X, Thakor J, Lu Z, Cai Y, Zhang Y, Mallona I, Peinado MA, Zahnow CA, Ahuja N, Fertig E, Issa JP, Baylin SB, Easwaran H.

Cancer Cell. 2019 Feb 11;35(2):315-328.e6. doi: 10.1016/j.ccell.2019.01.005.

Continue reading “Aging-like Spontaneous Epigenetic Silencing Facilitates Wnt Activation, Stemness, and BrafV600E-Induced Tumorigenesis”

Interplay between post-translational cyclooxygenase-2 modifications and the metabolic and proteomic profile in a colorectal cancer cohort.

Prieto P, Jaén RI, Calle D, Gómez-Serrano M, Núñez E, Fernández-Velasco M, Martín-Sanz P, Alonso S, Vázquez J, Cerdán S, Peinado MÁ, Boscá L.

World J Gastroenterol. 2019 Jan 28;25(4):433-446. doi: 10.3748/wjg.v25.i4.433.

Continue reading “Interplay between post-translational cyclooxygenase-2 modifications and the metabolic and proteomic profile in a colorectal cancer cohort.”

JOB POSITION: EPIGENOMICS BIOINFORMATICIAN (ref. 2018/113) [CLOSED]

Main Responsibilities

The individual in this position will be responsible for computational biology and bioinformatics support of genome-scale projects using advanced genomic technologies including in-house developed NGS methods. The major goal of the project is the obtention of genome-scale maps of epigenetic variation in human populations and disease. The project is highly collaborative and provides the opportunity to interact with investigators in different disciplines, including computational and experimental biology.

Primary duties will include, but will not be limited, to the design and implementation of algorithms to map, annotate, integrate and organize data generated by next generation sequencing instruments, and  downstream statistical analyses and validation. Duties will also include data-mining on high-throughput data sets and development of tools for data analysis, integration and visualization.

Requirements

Background: PhD in Bioinformatics, Computer Science, Biology,  Mathematics, or a related field. Experience in biomedical computing. Proven proficiency in the management of Biological Databases, programming languages (R, Perl, Java, C++, Python, etc.) and biostatistics methods is required.

What we offer

  • A contract for a period of 12 months with possibility of extension
  • Competitive salary according to qualifications and experience
  • Integration in a collaborative scientific network devoted to high quality research in the field of cancer genomics and epigenomics
  • Dynamic interaction with other leading cancer research groups
  • Interaction with other bioinformatics groups within and outside of the institution
  • Possibility for career advancement and attendance to specialized training courses and scientific meetings

Additional information

For more information on the research of the Mechanisms of Cancer and Cell Differentiation group visit the web page at http://maplab.cat or write to Miguel A. Peinado at mpeinado@igtp.cat.

Deadline for applications: 30 October 2018

How to apply

Interested applicants should send the following documents to rrhh@igtp.cat and mpeinado@igtp.cat:

  • A short statement of motivation
  • A CV including your contact details
  • Names, email and telephone numbers of two referees

 

PLEASE INDICATE THE REFERENCE 2018/113 in the subject of the mail.

DOWNLOAD ADVERTISEMENT: Job Offer

 

 

CpG Islands. Methods and Protocols

CpG islands constitute key genomic elements playing a fundamental role in essential biological processes such as development and cell differentiation. CpG islands are short stretches of DNA enriched in CpG dinucleotides, firstly identified by Adrian Bird in the 80’s. The human genome contains about 28,000 of these elements that are tightly associated to the regulation of 40% of the genes. Epigenetic alterations of specific CpG islands constitute molecular landmarks of multiple diseases including cancer, cardiovascular and neurological diseases, becoming principal targets as biomarkers and advanced therapeutic strategies.

The authoritative series Methods in Molecular Biology published by Springer Nature has released a new volume devoted to cover different aspects related with the study of these genomic elements. The book covers bioinformatic and molecular biology methods useful to identify and to explore the functions of CpG islands, as well as reviews on key applications of its study. Tanya Vavouri and Miguel A. Peinado, from the IJC and the IGTP, are the editors and have counted with the contribution of internationally renowned scientists in the fields of genomics and epigenomics.

The book contents and the online version may be found at: https://link.springer.com/book/10.1007/978-1-4939-7768-0.

Reference: Vavouri T, Peinado MA (ed.) CpG Islands: Methods and Protocols. Methods Mol Biol. 2018;1766. https://doi.org/10.1007/978-1-4939-7768-0

JOB POSITION: EPIGENOMICS BIOINFORMATICIAN (ref. 2017/05) [CLOSED]

We are assembling an interdisciplinary group to develop a collaborative project between academia and private entrepreneurship and welcome creative people from diverse backgrounds. Our project aims to bring the advances of Genomics and Epigenomics technologies to routine applications in health and biomedical research. Please visit our web sites for more information about our work.

DOWNLOAD ADVERTISEMENT: Job Offer

Requirements:

We are looking for a bionformatician to be responsible of the computational analysis of epigenetic changes in genome-scale projects using in-house developed next generation sequencing technology.  The ultimate goal of the project is the improvement of genomic tools to analyze genetic and epigenetic variations in cancer and other diseases.

A good background on the analysis of epigenetic modifications, especially methylation, using NGS technologies is highly desirable, as well as experience in job scheduling in grid/cloud computing. Proven proficiency in the management of Biological Databases, programming languages (R, Perl, C++, Python, etc.) and statistical methods is required.

Conditions: Salary will be internationally competitive.

How to apply: Please send your application to rrhh@igtp.cat and copy to: mpeinado@igtp.cat

Applications should include:

  • A CV including your contact details
  • Names, email and telephone number of at least two referees
  • A short statement of motivation

 

PLEASE QUOTE THE REFERENCE CODE ON ALL APPLICATIONS

Position posted: January 2017

Last date for Applications: 15th February 2017