JOB OFFER: EPIGENOMICS BIOINFORMATICIAN (ref. 2019/29) [CLOSED]

Main Responsibilities

The individual in this position will be responsible for computational biology and bioinformatics support of genome-scale projects using advanced genomic technologies including in-house developed NGS methods. The major goal of the project is the obtention of genome-scale maps of epigenetic variation in human populations and disease. The project is highly collaborative and provides the opportunity to interact with investigators in different disciplines, including computational and experimental biology.

Primary duties will include, but will not be limited, to the design and implementation of algorithms to map, annotate, integrate and organize data generated by next generation sequencing instruments, and  downstream statistical analyses and validation. Duties will also include data-mining on high-throughput data sets and development of tools for data analysis, integration and visualization.

Requirements

Background: PhD in Bioinformatics, Computer Science, Biology,  Mathematics, or a related field. Experience in biomedical computing. Proven proficiency in the management of Biological Databases, programming languages (R, Python, etc.) and biostatistics methods is required.

What we offer

  • A contract for a period of 12 months with possibility of extension
  • Competitive salary according to qualifications and experience
  • Integration in a collaborative scientific network devoted to high quality research in the field of cancer genomics and epigenomics
  • Dynamic interaction with other leading cancer research groups
  • Interaction with other bioinformatics groups within and outside of the institution
  • Possibility for career advancement and attendance to specialized training courses and scientific meetings

Additional information

For more information on the research of the Mechanisms of Cancer and Cell Differentiation group visit the web page at http://maplab.cat or write to Miguel A. Peinado at mpeinado@igtp.cat.

Deadline for applications: 24 March 2019

How to apply

Interested applicants should send the following documents to rrhh@igtp.cat and mpeinado@igtp.cat:

  • A short statement of motivation
  • A CV including your contact details
  • Names, email and telephone numbers of two referees

 

PLEASE INDICATE THE REFERENCE 2019/29 in the subject of the mail.

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JOB POSITION: Scientific Coordinator (ref. 2019/24) [CLOSED]

We are seeking an enthusiastic Scientific Coordinator to manage a collaborative project “GEUS” aimed to bring advances in Genomics and Epigenomics to research and medical applications. The project is a partnership between academic institutions and the biotech industry.

Continue reading “JOB POSITION: Scientific Coordinator (ref. 2019/24) [CLOSED]”

Aging-like Spontaneous Epigenetic Silencing Facilitates Wnt Activation, Stemness, and BrafV600E-Induced Tumorigenesis

Tao Y, Kang B, Petkovich DA, Bhandari YR, In J, Stein-O’Brien G, Kong X, Xie W, Zachos N, Maegawa S, Vaidya H, Brown S, Chiu Yen RW, Shao X, Thakor J, Lu Z, Cai Y, Zhang Y, Mallona I, Peinado MA, Zahnow CA, Ahuja N, Fertig E, Issa JP, Baylin SB, Easwaran H.

Cancer Cell. 2019 Feb 11;35(2):315-328.e6. doi: 10.1016/j.ccell.2019.01.005.

Continue reading “Aging-like Spontaneous Epigenetic Silencing Facilitates Wnt Activation, Stemness, and BrafV600E-Induced Tumorigenesis”

Interplay between post-translational cyclooxygenase-2 modifications and the metabolic and proteomic profile in a colorectal cancer cohort.

Prieto P, Jaén RI, Calle D, Gómez-Serrano M, Núñez E, Fernández-Velasco M, Martín-Sanz P, Alonso S, Vázquez J, Cerdán S, Peinado MÁ, Boscá L.

World J Gastroenterol. 2019 Jan 28;25(4):433-446. doi: 10.3748/wjg.v25.i4.433.

Continue reading “Interplay between post-translational cyclooxygenase-2 modifications and the metabolic and proteomic profile in a colorectal cancer cohort.”

JOB POSITION: EPIGENOMICS BIOINFORMATICIAN (ref. 2018/113) [CLOSED]

Main Responsibilities

The individual in this position will be responsible for computational biology and bioinformatics support of genome-scale projects using advanced genomic technologies including in-house developed NGS methods. The major goal of the project is the obtention of genome-scale maps of epigenetic variation in human populations and disease. The project is highly collaborative and provides the opportunity to interact with investigators in different disciplines, including computational and experimental biology.

Primary duties will include, but will not be limited, to the design and implementation of algorithms to map, annotate, integrate and organize data generated by next generation sequencing instruments, and  downstream statistical analyses and validation. Duties will also include data-mining on high-throughput data sets and development of tools for data analysis, integration and visualization.

Requirements

Background: PhD in Bioinformatics, Computer Science, Biology,  Mathematics, or a related field. Experience in biomedical computing. Proven proficiency in the management of Biological Databases, programming languages (R, Perl, Java, C++, Python, etc.) and biostatistics methods is required.

What we offer

  • A contract for a period of 12 months with possibility of extension
  • Competitive salary according to qualifications and experience
  • Integration in a collaborative scientific network devoted to high quality research in the field of cancer genomics and epigenomics
  • Dynamic interaction with other leading cancer research groups
  • Interaction with other bioinformatics groups within and outside of the institution
  • Possibility for career advancement and attendance to specialized training courses and scientific meetings

Additional information

For more information on the research of the Mechanisms of Cancer and Cell Differentiation group visit the web page at http://maplab.cat or write to Miguel A. Peinado at mpeinado@igtp.cat.

Deadline for applications: 30 October 2018

How to apply

Interested applicants should send the following documents to rrhh@igtp.cat and mpeinado@igtp.cat:

  • A short statement of motivation
  • A CV including your contact details
  • Names, email and telephone numbers of two referees

 

PLEASE INDICATE THE REFERENCE 2018/113 in the subject of the mail.

DOWNLOAD ADVERTISEMENT: Job Offer

 

 

Modular dynamics of DNA co-methylation networks exposes the functional organization of colon cancer cells’ genome

Izaskun Mallona, Susanna Ausso, Anna Diez-Villanueva, Victor MorenoMiguel A. Peinado

Continue reading “Modular dynamics of DNA co-methylation networks exposes the functional organization of colon cancer cells’ genome”

Adipose tissue mitochondrial dysfunction in human obesity is linked to a specific DNA methylation signature in adipose-derived stem cells

Ejarque M, Ceperuelo-Mallafré V, Serena C, Maymo-Masip E, Duran X, Díaz-Ramos A, Millan-Scheiding M, Núñez-Álvarez Y, Núñez-Roa C, Gama P, Garcia-Roves PM, Peinado MA, Gimble JM, Zorzano A, Vendrell J, Fernández-Veledo S.
Continue reading “Adipose tissue mitochondrial dysfunction in human obesity is linked to a specific DNA methylation signature in adipose-derived stem cells”